A Phi Beta Kappa and summa cum laude graduate of Arizona State University, Mark T. Worthington, M.D., obtained his medical education at Vanderbilt University, where he was elected to the Alpha Omega Alpha medical honorary and was awarded the Weinstein Award at graduation for "qualities that characterize the fine physician."
He did his internship, residency and gastroenterology fellowship training at the Johns Hopkins Hospital, Baltimore, Maryland, where he was chosen to be the Theodore Caldwell Janeway Assistant Chief of Service (Chief Resident). At Johns Hopkins, he did his fellowship research training in Molecular Biology and Genetics in the laboratory of Daniel Nathans, 1978 recipient of the Nobel Prize in Medicine, then spent 14 years in academic medicine, with 10 years on the faculty at the University of Virginia and 4 years back at Johns Hopkins.
His research interests centered around inflammatory bowel disease and iron absorption in the intestine. At the University of Virginia, he was awarded the AGA Research Scholar Award, The University of Virginia Teaching Award, and Fellowship in the American Gastroenterology Association. He was a member of UVA's Institutional Review Board, which protects the rights and welfare of patients involved in clinical studies. Back at Johns Hopkins, he participated in a large-scale review of all of the clinical drugs used for inflammatory bowel disease for the Agency for Healthcare Research and Quality; he also served four years on the American Board of Internal Medicine committee that writes the test questions for Internist Board Certification. He is the author of numerous scientific papers, including publications in Cell and the Proceedings of the National Academy of Sciences, and several textbook chapters, including in the Advanced Inflammatory Bowel Disease textbook. In 2010, Dr. Worthington returned to Arizona, where he has consistently been listed as a Castle Connolly Top Doctor in Gastroenterology, and in 2016, he was named Yavapai Regional Medical Center's Physician of the Year.
Dr. Worthington is married, with three children, three dogs, and a small flock of ducks and chickens. His wife, Janet, is an author who has won numerous awards for her health writing. In his free time, Dr. Worthington enjoys fly fishing, skiing, kayaking, hiking, experimenting with music electronics, visiting his Wyoming family, and playing music. He firmly believes he is the first person ever to have fly fishing waders drying in the Johns Hopkins Hospital, after he discovered there were 7 fishable trout streams within a half-hour drive of that institution.